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Article

Angiotensinogen promoter variants influence gene expression in human kidney and visceral adipose tissue.

Journal of human hypertension - 1 Mar 2010

Sarzani R, Bordicchia M, Marcucci P, Minardi D, Muzzonigro G, Dessì-Fulgheri P, Rappelli A

Abstract excerpt

Human angiotensinogen (AGT) gene promoter polymorphisms (G-217A; A-20C; G-6A) influence AGT transcription in vitro and have been implicated in the genetics of essential hypertension. We analysed the association among AGT promoter variants and AGT mRNA levels in human kidney and visceral adipose tissue (VAT) in vivo. Samples of kidney and VAT were obtained from 35 consecutive patients undergoing renal surgery. The...

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Share to Angiotensinogen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Renal

Share to Intra-Abdominal Fat

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 19536167
DOI: 10.1038/jhh.2009.48

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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