Article
Essential hypertension and 5' upstream core promoter region of human angiotensinogen gene.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 1997
Ishigami T, Umemura S, Tamura K, Hibi K, Nyui N, Kihara M, Yabana M, Watanabe Y, Sumida Y, Nagahara T, Ochiai H, Ishii M
Abstract excerpt
The angiotensinogen (AGT) gene M235T variant is associated with essential hypertension and elevated plasma AGT concentrations, although the underlying mechanisms are unknown. Recent studies have suggested that AGCE 1 (human AGT gene core promoter element 1) located in the 5' upstream core promote...
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