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Article

A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 2005

Jain Sudhir, Li Yanna, Patil Sai, Kumar Ashok

Abstract excerpt

Hypertension is a serious health problem particularly for African-Americans. Previous studies have suggested that angiotensinogen (AGT) gene locus is involved in human essential hypertension. We have recently shown that an A/G polymorphism at -217 in the promoter of the AGT gene is associated with essential hypertension especially in African-Americans. We report here that A/G polymorphism at -217 affects the...

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Source

Identifiers

PMID: 15630592
DOI: 10.1007/s00109-004-0621-5

Genes

AGT
EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A single-nucleotide polymorphism in human angiotensinogen gene is associated with essential hypertension and affects glucocorticoid induced promoter activity.PMID 15630592Read ↗

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A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G.Semantic proximity Read ↗

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Dexamethasone promotes hypertension by allele-specific regulation of the human angiotensinogen gene.Semantic proximity Read ↗

Angiotensinogen promoter sequence variants in essential hypertension.Semantic proximity Read ↗

A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro.Semantic proximity Read ↗

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