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Article

Variants in blood pressure genes and the risk of renal cell carcinoma.

Carcinogenesis - 1 Apr 2010

Andreotti Gabriella, Boffetta Paolo, Rosenberg Philip S, Berndt Sonja I, Karami Sara, Menashe Idan, Yeager Meredith, Chanock Stephen J, Zaridze David, Matteev Vsevolod, Janout Vladimir, Kollarova Hellena, Bencko Vladimir, Navratilova Marie, Szeszenia-Dabrowska Neonilia, Mates Dana, Rothman Nathaniel, Brennan Paul, Chow Wong-Ho, Moore Lee E

Abstract excerpt

Hypertension is a known risk factor for renal cell carcinoma (RCC), although the underlying biological mechanisms of its action are unknown. To clarify the role of hypertension in RCC, we examined the risk of RCC in relation to 142 single-nucleotide polymorphisms (SNPs) in eight genes having a role in blood pressure control. We analyzed 777 incident and histologically confirmed RCC cases and 1035 controls who...

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Identifiers

PMID: 20047954
DOI: 10.1093/carcin/bgp321
PMCID: PMC2847086

Genes

AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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