Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.

American journal of physiology. Renal physiology - 1 Sept 2009

Schaier Matthias, Vorwalder Stefanie, Sommerer Claudia, Dikow Ralf, Hug Friederike, Gross Marie-Luise, Waldherr Rüdiger, Zeier Martin

Abstract excerpt

Renal injury is accompanied by the presence of infiltrating inflammatory cells in the glomerulus and tubulointerstitium. FTY720 modifies lymphocyte migration into injured tissues by lymphocyte sequestration to secondary lymphoid organs. The purpose of this study was to examine the potential of FTY720 to influence the inflammatory response in a nonimmunological model of renal failure. Sham-operated and 5/6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Chemokine CCL2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CCL5

Share to Creatinine

Share to Nephrectomy

Share to Nephritis

Share to Receptors, CCR2

Share to Sphingosine

Source

Identifiers

PMID: 19535570
DOI: 10.1152/ajprenal.90530.2008

Genes

CCR1
CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.PMID 19535570Read ↗

Pirfenidone inhibits macrophage infiltration in 5/6 nephrectomized rats.Semantic proximity Read ↗

Glomerular Macrophages in Human Auto- and Allo-Immune Nephritis.Semantic proximity Read ↗

Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease.Semantic proximity Read ↗

Contrasting effects of systemic monocyte/macrophage and CD4+ T cell depletion in a reversible ureteral obstruction mouse model of chronic kidney disease.Semantic proximity Read ↗

CD4+CD25+ regulatory T cells protect against injury in an innate murine model of chronic kidney disease.Semantic proximity Read ↗

Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease.Semantic proximity Read ↗

The glomerulosclerosis of aging in females: contribution of the proinflammatory mesangial cell phenotype to macrophage infiltration.Semantic proximity Read ↗

Alternatively activated macrophages in the pathogenesis of chronic kidney allograft injury.Semantic proximity Read ↗

Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis.Semantic proximity Read ↗

IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis.Semantic proximity Read ↗

Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD.Semantic proximity Read ↗

GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.