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Article

Conversion of linear DNA with hairpin telomeres into a circular molecule in the course of phage N15 lytic replication.

Journal of molecular biology - 14 Aug 2009

Mardanov Andrey V, Ravin Nikolai V

Abstract excerpt

The prophage of temperate coliphage N15 is not integrated into the bacterial chromosome but exists as a linear plasmid molecule with covalently closed ends. Upon infection of an Escherichia coli cell, the phage DNA circularises via cohesive ends. A phage-encoded enzyme, protelomerase, then cuts at another site, telRL, and forms hairpin ends (telomeres) of linear plasmid prophage. Bidirectional replication of a...

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Identifiers

PMID: 19523475
DOI: 10.1016/j.jmb.2009.06.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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