Article
Role of nucleotidyl transferase motif V in strand joining by chlorella virus DNA ligase.
The Journal of biological chemistry - 22 Mar 2002
Sriskanda Verl, Shuman Stewart
Abstract excerpt
ATP-dependent DNA ligases, NAD(+)-dependent DNA ligases, and GTP-dependent RNA capping enzymes are members of a covalent nucleotidyl transferase superfamily defined by a common fold and a set of conserved peptide motifs. Here we examined the role of nucleotidyl transferase motif V ((184)LLKMKQFKDAEAT(196)) in the nick joining reaction of Chlorella virus DNA ligase, an exemplary ATP-dependent enzyme. We found that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
