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Article

On the origin of telomeres: a glimpse at the pre-telomerase world.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2006

Nosek Jozef, Kosa Peter, Tomaska Lubomir

Abstract excerpt

Chromosomes may be either circular or linear, the latter being prone to erosion caused by incomplete replication, degradation and inappropriate repair. Despite these problems, the linear form of DNA is frequently found in viruses, bacteria, eukaryotic nuclei and organelles. The high incidence of linear chromosomes and/or genomes evokes why and how they emerged in evolution. Here we suggest that the primordial...

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Identifiers

PMID: 16435294
DOI: 10.1002/bies.20355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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