Article
Functional characterization of the repA replication gene of linear plasmid prophage N15.
Research in microbiology - 1 Mar 2006
Mardanov Andrey V, Ravin Nikolai V
Abstract excerpt
The prophage of coliphage N15 is not integrated into the chromosome, but exists as a linear plasmid molecule with covalently closed ends. The only phage gene required for replication of circular N15 miniplasmids is repA (gene 37). Here we show that RepA-driven replication of the N15-based circular and linear miniplasmids is independent of host DnaB helicase protein, but requires the host DnaG primase. Replication...
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