Article
Bidirectional replication from an internal ori site of the linear N15 plasmid prophage.
Nucleic acids research - 15 Nov 2003
Ravin Nikolai V, Kuprianov Victor V, Gilcrease Eddie B, Casjens Sherwood R
Abstract excerpt
The prophage of coliphage N15 is not integrated into the chromosome but exists as a linear plasmid molecule with covalently closed hairpin ends (telomeres). Upon infection the injected phage DNA circularizes via its cohesive ends. Then, a phage-encoded enzyme, protelomerase, cuts the circle and forms the hairpin telomeres. N15 protelomerase acts as a telomere-resolving enzyme during prophage DNA replication. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.