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Article

Sequence requirements for the termination of rolling-circle replication of plasmid pT181.

Molecular microbiology - 1 May 1997

Zhao A C, Khan S A

Abstract excerpt

Most small multicopy plasmids of Gram-positive bacteria and many in Gram-negative bacteria replicate by a rolling-circle (RC) mechanism. The replication initiator proteins encoded by the RC plasmids and single-stranded bacteriophages of Escherichia coli have origin-specific nicking-closing activities that are required for the initiation and termination of RC replication. We have investigated the sequence...

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Source

Identifiers

PMID: 9179847
DOI: 10.1046/j.1365-2958.1997.3641730.x

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