Article
Analysis of a promoter polymorphism in the SMDF neuregulin 1 isoform in Schizophrenia.
Neuropsychobiology - 1 Jan 2009
Pedrosa Erika, Nolan Karen A, Stefanescu Radu, Herskovits Pnina, Hershcovitz Pnina, Novak Tomas, Zukov Ilja, Stopkova Pavla, Lachman Herbert M
Abstract excerpt
BACKGROUND/AIMS: Neuregulin 1 (NRG1) is a positional candidate gene in schizophrenia (SZ). Two major susceptibility loci in the NRG1 gene approximately one million nucleotides apart have been identified in genetic studies. Several candidate functional allelic variants have been described that might be involved in disease susceptibility. However, the findings are still preliminary. We recently mapped active...
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