Article
Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population.
Molecular psychiatry - 1 Jan 2007
Thomson P A, Christoforou A, Morris S W, Adie E, Pickard B S, Porteous D J, Muir W J, Blackwood D H R, Evans K L
Abstract excerpt
Neuregulin 1 (NRG1) is a strong candidate for involvement in the aetiology of schizophrenia. A haplotype, initially identified as showing association in the Icelandic and Scottish populations, has shown a consistent effect size in multiple European populations. Additionally, NRG1 has been implicated in susceptibility to bipolar disorder. In this first study to select markers systematically on the basis of linkage...
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