Article
Support for involvement of neuregulin 1 in schizophrenia pathophysiology.
Molecular psychiatry - 1 Apr 2005
Petryshen T L, Middleton F A, Kirby A, Aldinger K A, Purcell S, Tahl A R, Morley C P, McGann L, Gentile K L, Rockwell G N, Medeiros H M, Carvalho C, Macedo A, Dourado A, Valente J, Ferreira C P, Patterson N J, Azevedo M H, Daly M J, Pato C N, Pato M T, Sklar P
Abstract excerpt
Schizophrenia is a common, multigenic psychiatric disorder. Linkage studies, including a recent meta-analysis of genome scans, have repeatedly implicated chromosome 8p12-p23.1 in schizophrenia susceptibility. More recently, significant association with a candidate gene on 8p12, neuregulin 1 (NRG1...
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