Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and Functional Studies of Regulatory Variants Responsible for the Association of NRG3 with a Delusion Phenotype in Schizophrenia

1 Jan 2015

Abstract excerpt

We previously reported a genetic linkage for schizophrenia (SZ; nonparametric linkage score of 4.27) at 10q22 in an Ashkenazi Jewish (AJ) population. In follow-up fine-mapping, we found strong evidence for an association between 3 intronic single nucleotide variants (SNVs) in the 5′ end of neuregulin 3 (NRG3) and the delusion factor score of our phenotypic principal component analysis. Two independent groups...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Associations and Epidemiology
Share to HER2/EGFR in Cancer Research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26528484
DOI: 10.1159/000371518

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and Functional Studies of Regulatory Variants Responsible for the Association of NRG3 with a Delusion Phenotype in SchizophreniaPMID 26528484Read ↗

Fine mapping on chromosome 10q22-q23 implicates Neuregulin 3 in schizophrenia.Semantic proximity Read ↗

Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain.Semantic proximity Read ↗

Analysis of a promoter polymorphism in the SMDF neuregulin 1 isoform in Schizophrenia.Semantic proximity Read ↗

Meta-analysis reveals associations between genetic variation in the 5' and 3' regions of Neuregulin-1 and schizophrenia.Semantic proximity Read ↗

Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Neuregulin 3 and its roles in schizophrenia risk and presentation.Semantic proximity Read ↗

Mendelian randomization facilitates identification of schizophrenia risk enhancer RNAs.Semantic proximity Read ↗

Neuregulin 3 does not confer risk for schizophrenia and smooth pursuit eye movement abnormality in a Korean population.Semantic proximity Read ↗

Genetic and functional analysis of the gene encoding neurogranin in schizophrenia.Semantic proximity Read ↗

Support for neuregulin 1 as a susceptibility gene for bipolar disorder and schizophrenia.Semantic proximity Read ↗

Neuregulin 3 (NRG3) as a susceptibility gene in a schizophrenia subtype with florid delusions and relatively spared cognition.Semantic proximity Read ↗

Analysis of neurogranin (NRGN) in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.