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Article

Blocked inhibitory serine-phosphorylation of glycogen synthase kinase-3alpha/beta impairs in vivo neural precursor cell proliferation.

Biological psychiatry - 1 Sept 2009

Eom Tae-Yeon, Jope Richard S

Abstract excerpt

BACKGROUND: Adult neurogenesis augments neuronal plasticity, and deficient neurogenesis might contribute to mood disorders and schizophrenia and impede treatment responses. Because these diseases might be associated with inadequately controlled glycogen synthase kinase-3 (GSK3), we tested whether blocked inhibitory serine-phosphorylation of GSK3 impairs neurogenesis. METHODS: Neural precursor cell (NPC)...

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Identifiers

PMID: 19520363
DOI: 10.1016/j.biopsych.2009.04.015
PMCID: PMC2746934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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