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Article

Loss of GSK-3 Causes Abnormal Astrogenesis and Behavior in Mice.

Molecular neurobiology - 1 Aug 2016

Jung Eui-Man, Ka Minhan, Kim Woo-Yang

Abstract excerpt

Altered activity of glycogen synthase kinase-3 (GSK-3) is associated with psychiatric diseases and neurodegenerative diseases. GSK-3 is a key regulator in multiple aspects of neuronal differentiation in the brain. However, little is known about the role of GSK-3 in astrocyte development. To examine the role of GSK-3 in astrocytes, we generated a conditional knockout mouse using a glial fibrillary acidic protein...

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Source

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Identifiers

PMID: 26179612
DOI: 10.1007/s12035-015-9326-8
PMCID: PMC4716001

Genes

GFAP
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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