Article
Association of polymorphisms in estrogen and thyroid hormone receptors with thyroid cancer risk.
Journal of receptor and signal transduction research - 1 Jan 2009
Rebaï Maha, Kallel Imen, Charfeddine Salma, Hamza Fatma, Guermazi Fadhel, Rebaï Ahmed
Abstract excerpt
The receptors for thyroid hormone (THR) and oestrogen (ESR) are prototypes of nuclear transcription factors that regulate the expression of target genes. Genetic alterations in the genes of these receptors were found to be involved in cancer development. In this study we investigated the association of one SNP (rs2228480, T594T) and one microsatellite marker (D6S440) within the ESR1 gene and a dinucleotide repeat...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
