Article
Polymorphisms in the promoter region of ESR2 gene and susceptibility to ovarian cancer.
Gene - 10 Aug 2014
Schüler Susanne, Lattrich Claus, Skrzypczak Maciej, Fehm Tanja, Ortmann Olaf, Treeck Oliver
Abstract excerpt
Susceptibility to ovarian cancer might be affected by genetic variations in genes involved in estrogen biosynthesis, metabolism or signal transduction. In this study we tested the hypothesis that single nucleotide polymorphisms (SNPs) in the promoter of human ESR2 gene, coding for estrogen receptor β, may be associated with increased risk for ovarian cancer. Three SNPs in the promoter region of human ESR2 gene...
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