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Article

Polymorphisms in the promoter region of estrogen receptor β gene in endometrial cancer.

Archives of gynecology and obstetrics - 1 Mar 2014

Lattrich Claus, Häring Julia, Schüler Susanne, Skrzypczak Maciej, Ortmann Olaf, Treeck Oliver

Abstract excerpt

INTRODUCTION: The development of endometrial cancer is known to be affected by estrogens. Thus, genetic variations like single nucleotide polymorphisms (SNPs) in genes involved in estrogen biosynthesis, metabolism, and signal transduction might affect risk for endometrial cancer. In this study, we tested the hypothesis that polymorphisms in the promoter of ESR2 gene may be associated with susceptibility to this...

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PMID: 23974281
DOI: 10.1007/s00404-013-3012-8

Genes

ESR2

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