Article
Polymorphisms in the promoter region of ESR2 gene and breast cancer susceptibility.
The Journal of steroid biochemistry and molecular biology - 1 Apr 2009
Treeck Oliver, Elemenler Esma, Kriener Christina, Horn Felicitas, Springwald Anette, Hartmann Arndt, Ortmann Olaf
Abstract excerpt
Genetic variations like single nucleotide polymorphisms (SNPs) in genes involved in estrogen biosynthesis, metabolism and signal transduction have been suggested to affect breast cancer susceptibility. In this study we tested the hypothesis that polymorphisms in the promoter of ESR2 gene may be associated with increased risk for breast cancer. We analyzed three SNPs in the promoter region of human ESR2 gene by...
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