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Article

A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women.

Carcinogenesis - 1 Jan 2009

Tchatchou Sandrine, Jung Anke, Hemminki Kari, Sutter Christian, Wappenschmidt Barbara, Bugert Peter, Weber Bernhard H F, Niederacher Dieter, Arnold Norbert, Varon-Mateeva Raymonda, Ditsch Nina, Meindl Alfons, Schmutzler Rita K, Bartram Claus R, Burwinkel Barbara

Abstract excerpt

MicroRNAs (miRNAs) negatively regulate expression of target transcripts by hybridization to complementary sites of their messenger RNA targets. Chen et al. have described several putative functional single nucleotide polymorphisms (SNPs) in miRNA target sites. Here, we selected 11 miRNA target site SNPs located in 3' untranslated regions of genes involved in cancer and breast cancer to analyze their impact on...

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Source

Identifiers

PMID: 19028706
DOI: 10.1093/carcin/bgn253

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A variant affecting a putative miRNA target site in estrogen receptor (ESR) 1 is associated with breast cancer risk in premenopausal women.PMID 19028706Read ↗

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