Article
Association of EGFR and HER2 polymorphisms with risk and clinical features of thyroid cancer.
Genetic testing and molecular biomarkers - 1 Dec 2009
Rebaï Maha, Kallel Imen, Hamza Fatma, Charfeddine Salma, Kaffel Raja, Guermazi Fadhel, Rebaï Ahmed
Abstract excerpt
The epidermal growth factor receptor family plays a critical role in the control of many physiological processes. Genetic alterations and/or variations in the gene encoding these receptors have been implicated in a variety of human cancers. In this study we evaluate the association of two single-nucleotide polymorphisms (SNP), R497K and I655V, of the EGFR and HER2 genes, respectively, with thyroid cancer risk....
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