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Article

Association of a functional polymorphism (C59038T) in GTP cyclohydrolase 1 gene and Type 2 diabetic macrovascular disease in the Chinese population.

Journal of diabetes and its complications - 1 Jan 2000

Liao Yun-fei, Zeng Tian-shu, Chen Lu-Lu, Li Yu-ming, Yu Fan, Hu Li-jun, Yue Ling

Abstract excerpt

Nitric oxide (NO) unavailability plays an important role in the progression of macrovascular diseases in Type 2 diabetes (T2DM). C59038T polymorphism in GTP cyclohydrolase 1 (GCH1) gene is a functional mutation involved in NO metabolism and cardiovascular risk in a multiethnic population. To clarify the relationship between C59038T polymorphism and macrovascular disease in T2DM, an association study was performed...

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Source

Identifiers

PMID: 19515581
DOI: 10.1016/j.jdiacomp.2009.04.003

Genes

GCH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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