Article
Interactive effects of a common γ-glutamyltransferase 1 variant and low high-density lipoprotein-cholesterol on diabetic macro- and micro-angiopathy.
Cardiovascular diabetology - 8 May 2015
Jinnouchi Hideaki, Morita Kazunori, Tanaka Takahiro, Kajiwara Ayami, Kawata Yuki, Oniki Kentaro, Saruwatari Junji, Nakagawa Kazuko, Otake Koji, Ogata Yasuhiro, Yoshida Akira, Hokimoto Seiji, Ogawa Hisao
Abstract excerpt
BACKGROUND: We investigated the clinical relevance of a common variant, rs4820599, in the γ-glutamyltransferase (GGT)1 gene, associated with the serum GGT level, in Japanese type 2 diabetes mellitus (T2DM) subjects. METHODS: We conducted a retrospective longitudinal study (4.9 ± 2.5 years) including 352 T2DM patients (T2DM subjects) and a cross-sectional study including 796 health screening program participants...
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