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Article

Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients.

Molecular and cellular biochemistry - 1 Jul 2011

Jafari Yazdan, Rahimi Zohreh, Vaisi-Raygani Asad, Rezaei Mansour

Abstract excerpt

The present study has investigated the role of endothelial nitric oxide (eNOS) G894T polymorphism and its interaction with methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C variants on the predisposition to diabetic nephropathy and its progression. Using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method the eNOS G894T and MTHFR polymorphisms were detected in 72...

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Share to Albuminuria
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Epistasis, Genetic

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Nitric Oxide Synthase Type III

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Source

Identifiers

PMID: 21380725
DOI: 10.1007/s11010-011-0770-0

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of eNOS polymorphism with MTHFR variants increase the risk of diabetic nephropathy and its progression in type 2 diabetes mellitus patients.PMID 21380725Read ↗

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