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Nitric oxide system and diabetic nephropathy

12 Feb 2014

Abstract excerpt

About 30% of patients with type 2 diabetes mellitus develop clinically overt nephropathy. Hyperglycemia is necessary, but not sufficient, to cause the renal damage that leads to kidney failure. Diabetic nephropathy (DN) is a multifactorial disorder that results from interaction between environmental and genetic factors. In the present article we will review the role of the nitric oxide synthase (NOS) in the...

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PMID: 24520999
DOI: 10.1186/1758-5996-6-17

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