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Article

Single nucleotide polymorphisms in monocyte chemoattractant protein-1 and its receptor act synergistically to increase the risk of carotid atherosclerosis.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2009

Nyquist Paul A, Winkler Cherie A, McKenzie Louise M, Yanek Lisa R, Becker Lewis C, Becker Diane M

Abstract excerpt

BACKGROUND: Monocyte chemoattractant protein 1 (MCP-1), acting in concert with its receptor chemokine receptor 2 (CCR2), promotes recruitment of macrophages into atherosclerotic plaque. We examined whether single nucleotide polymorphism (SNP) variants in the MCP-1 or CCR2 genes independently or in combination are associated with carotid artery atherosclerosis in an African American population at increased risk of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19506371
DOI: 10.1159/000223437
PMCID: PMC2914430

Genes

CCR2

Variants

rs1799864

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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