Article
Genomewide linkage and peakwide association analyses of carotid plaque in Caribbean Hispanics.
Stroke - 1 Dec 2010
Dong Chuanhui, Beecham Ashley, Slifer Susan, Wang Liyong, Blanton Susan H, Wright Clinton B, Rundek Tatjana, Sacco Ralph L
Abstract excerpt
BACKGROUND AND PURPOSE: Atherosclerosis is a complex subclinical cardiovascular disorder with a substantial genetic component. This study sought to identify genetic loci influencing carotid plaque in 2 independent samples. METHODS: B-mode ultrasound was performed to determine the presence and area of carotid plaque. Variance components analysis was used to test for linkage using 383 autosomal microsatellite...
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