Article
A monocyte chemoattractant protein-1 gene polymorphism is associated with occult ischemia in a high-risk asymptomatic population.
Atherosclerosis - 1 Aug 2007
Kim Min P, Wahl Larry M, Yanek Lisa R, Becker Diane M, Becker Lewis C
Abstract excerpt
Monocyte chemoattractant protein-1 (MCP-1) recruits monocytes into atherosclerotic plaques. A single nucleotide polymorphism in the MCP-1 gene promoter (-2578A>G) results in greater production of MCP-1 protein. We examined the association of this polymorphism with occult coronary artery disease (CAD) and its interaction with CAD risk factor burden, as assessed by the Framingham risk score (FRS) for hard events....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
