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Article

Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics.

Journal of the neurological sciences - 15 Sept 2014

Della-Morte David, Wang Liyong, Beecham Ashley, Blanton Susan H, Zhao Hongyu, Sacco Ralph L, Rundek Tatjana, Dong Chuanhui

Abstract excerpt

BACKGROUND AND PURPOSE: Smoking greatly increases the risk of atherosclerotic plaque and the effect may vary from individual to individual. A genome-wide scan was performed for smoking×single nucleotide polymorphism (SNP) interactions on carotid plaque burden (CPB) to identify the potential genetic moderators in Hispanics. METHODS: Carotid B-mode ultrasonography and genotyping by the Affymetrix 6.0 chip were...

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Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hispanic or Latino

Share to Membrane Proteins

Share to Plaque, Atherosclerotic

Share to Repressor Proteins

Share to Smoking

Share to Statistics, Nonparametric

Source

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Identifiers

PMID: 24954085
DOI: 10.1016/j.jns.2014.06.006
PMCID: PMC4143440

Genes

JPH1
MXD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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