Article
Genetic control of chemokines in severe human internal carotid artery stenosis.
Cytokine - 1 Jan 2008
Ghilardi Giorgio, Biondi Maria Luisa, Turri Olivia, Pateri Francesca, d'Eril Gianvico Melzi, Scorza Roberto
Abstract excerpt
BACKGROUND AND PURPOSE: Atherosclerosis is an inflammatory disease. Chemokines and chemokine receptors are known to be involved in atherogenesis. Common single nucleotide polymorphisms (SNPs) affect transcription in response to inflammatory stimuli. The aim of this study was to evaluate the correlations between MCP-1, RANTES, SDF-1, CCR2, and CCR5 gene polymorphisms with increased risk of internal carotid artery...
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