Article
Atherosclerosis in patients infected with HIV is influenced by a mutant monocyte chemoattractant protein-1 allele.
Circulation - 12 Oct 2004
Alonso-Villaverde Carlos, Coll Blai, Parra Sandra, Montero Manuel, Calvo Nahum, Tous Mònica, Joven Jorge, Masana Lluis
Abstract excerpt
BACKGROUND: Patients infected with HIV present with premature atherosclerosis, and the 2 diseases share common pathogenic pathways. We investigated mutations in the monocyte chemoattractant protein-1 (MCP-1) and CCR-2 genes, which are known to control aspects of these pathways, to ascertain wheth...
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