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Article

Gene single nucleotide polymorphism accumulation improves survival in advanced head and neck cancer patients treated with weekly paclitaxel.

The Laryngoscope - 1 Aug 2009

Grau Juan J, Caballero Miguel, Campayo Marc, Jansa Sonia, Vargas Mauricio, Alós Llucia, Monzo Mariano

Abstract excerpt

OBJECTIVES/HYPOTHESIS: Single nucleotide polymorphisms (SNPs) of certain genes involved in drug metabolism correlate with survival. METHODS: We evaluated the presence of SNPs in six genes (CYP2C8, GSTT1, GSTP1, MDR1-57, MDR1-62, and ERCC1) and the response rate (RR), time to progression (TTP), an...

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Source

Identifiers

PMID: 19504558
DOI: 10.1002/lary.20254

Genes

ERCC1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19504558-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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