Article
Rat G protein-coupled receptor kinase GRK4: identification, functional expression, and differential tissue distribution of two splice variants.
Endocrinology - 1 Jun 1998
Virlon B, Firsov D, Cheval L, Reiter E, Troispoux C, Guillou F, Elalouf J M
Abstract excerpt
G protein-coupled receptor kinases (GRKs) specifically phosphorylate the agonist-occupied form of G protein-coupled receptors, leading to the homologous mode of desensitization. We report here on the cloning of complementary DNAs that encode two rat GRK4 variants. Rat GRK4A (575 amino acids) disp...
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