BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels.

doi:10.1002/hbm.22630

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Article

BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels.

Human brain mapping - 1 Jan 2015

Fisher Patrick M, Holst Klaus K, Adamsen Dea, Klein Anders Bue, Frokjaer Vibe G, Jensen Peter S, Svarer Claus, Gillings Nic, Baare William F C, Mikkelsen Jens D, Knudsen Gitte M

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) has been implicated in multiple aspects of brain function including regulation of serotonin signaling. The BDNF val66met polymorphism (rs6265) has been linked to aspects of serotonin signaling in humans but its effects are not well understood. To address this, we evaluated whether BDNF val66met was predictive of a putative marker of brain serotonin levels, serotonin 4...

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PMID: 25220079
DOI: 10.1002/hbm.22630
PMCID: PMC6869129

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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