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Article

Serotonin transporter gene polymorphisms: effect on serotonin transporter availability in the brain of suicide attempters.

Psychiatry research - 15 Apr 2008

Bah Jessica, Lindström Mats, Westberg Lars, Mannerås Louise, Ryding Erik, Henningsson Susanne, Melke Jonas, Rosén Ingmar, Träskman-Bendz Lil, Eriksson Elias

Abstract excerpt

The efficacy of serotonin reuptake inhibitors in depression and anxiety disorders suggests the gene coding for the serotonin transporter (5-HTT), SLC6A4, as a candidate of importance for these conditions. Positive findings regarding associations between polymorphisms in SLC6A4 have been reported, indicating that these polymorphisms may influence anxiety-related personality traits, as well as the risk of...

Topics

Adult
Alleles
Brain
Gene Expression
Gene Frequency
Humans
Introns
Male
Minisatellite Repeats
Polymorphism, Genetic
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Self-Injurious Behavior

Serotonin Plasma Membrane Transport Proteins

Suicide, Attempted

Tomography, Emission-Computed, Single-Photon

Source

Identifiers

PMID: 18314311
DOI: 10.1016/j.pscychresns.2007.07.004

Genes

HTT
CIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18314311-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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