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Article

The anterior cingulate ERK pathway contributes to regulation of behavioral excitement and hedonic activity.

Bipolar disorders - 1 Jun 2009

Creson Thomas K, Hao Yanlei, Engel Sharon, Shen Yi, Hamidi Anahita, Zhuo Min, Manji Husseini K, Chen Guang

Abstract excerpt

OBJECTIVES: Several intracellular signaling cascades, such as the extracellular signal-regulated kinase (ERK), Wnt-signaling/GSK-3, PLC/PKC, and PI3K pathways, have been shown to be affected directly or indirectly by mood stabilizers. Clinical imaging studies reveal that mood disorders are associated with structural and/or metabolic changes in specific brain regions such as the anterior cingulate cortex (ACC)....

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Identifiers

PMID: 19500087
DOI: 10.1111/j.1399-5618.2009.00697.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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