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Article

FXR1P is a GSK3β substrate regulating mood and emotion processing.

Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 2015

Del'Guidice Thomas, Latapy Camille, Rampino Antonio, Khlghatyan Jivan, Lemasson Morgane, Gelao Barbara, Quarto Tiziana, Rizzo Giuseppe, Barbeau Annie, Lamarre Claude, Bertolino Alessandro, Blasi Giuseppe, Beaulieu Jean-Martin

Abstract excerpt

Inhibition of glycogen synthase kinase 3β (GSK3β) is a shared action believed to be involved in the regulation of behavior by psychoactive drugs such as antipsychotics and mood stabilizers. However, little is known about the identity of the substrates through which GSK3β affects behavior. We identified fragile X mental retardation-related protein 1 (FXR1P), a RNA binding protein associated to genetic risk for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26240334
DOI: 10.1073/pnas.1506491112
PMCID: PMC4547302

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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