Possible involvement of the ERK signaling cascade in bipolar disorder: Behavioral leads from the study of mutant mice

Abstract excerpt

Despite the devastating impact that bipolar disorder has on the lives of millions worldwide, little is known for certain about its etiology or pathophysiology. Whereas research has traditionally focused on biogenic amines, it is becoming increasingly more apparent that intracellular pathways are involved in the etiology and treatment of the disease and that a true understanding of the pathophysiology of bipolar...

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