Article
A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine.
Psychopharmacology - 1 May 2009
Bryant Camron D, Graham Melissa E, Distler Margaret G, Munoz Michaelanne B, Li Dongdong, Vezina Paul, Sokoloff Greta, Palmer Abraham A
Abstract excerpt
RATIONALE: We previously colocalized a quantitative trait locus (QTL) for sensitivity to the locomotor stimulant effects of methamphetamine (MA) with a QTL for expression of casein kinase 1 epsilon (Csnk1-epsilon) in the nucleus accumbens (NAc). Subsequently, we identified a single nucleotide polymorphism in CSNK1E (rs135745) that was associated with increased sensitivity to the subjective effects of...
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