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Article

Dissecting the genetic basis of kidney tubule response to hyperoxaluria using chromosome substitution strains.

American journal of physiology. Renal physiology - 1 Aug 2009

Wiessner John H, Garrett Michael R, Roman Richard J, Mandel Neil S

Abstract excerpt

Whether genetics may play a role in the pathophysiologic response of kidney tubules to oxalate exposure remains unexplored despite that as many as 15% of the U.S. population annually will experience a kidney stone composed of calcium oxalate. To explore this issue, we utilized a panel of chromosome substitution strains in which one chromosome at a time was transferred from the Brown Norway (BN) rat onto the Dahl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19493966
DOI: 10.1152/ajprenal.00009.2009
PMCID: PMC2724241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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