Article
Competitive capacity of HIV-1 strains carrying M184I or Y181I drug-resistant mutations.
Chinese medical journal - 5 May 2009
Li Jue, Li Lin, Li Han-ping, Zhuang Dao-min, Liu Si-yang, Liu Yong-jian, Bao Zuo-yi, Wang Zheng, Li Jing-yun
Abstract excerpt
BACKGROUND: Virus with nucleoside reverse transcriptase inhibitors (NRTIs) or nonnucleoside reverse transcriptase inhibitors (NNRTIs) resistant mutations show different evolution tendencies when the anti-viral therapies are interrupted. Understanding the replication fitness of drug-resistant virus is important for the study of the prevalence of drug-resistance. For this purpose, we characterized the replication...
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