Article
Differential impact of resistance-associated mutations to protease inhibitors and nonnucleoside reverse transcriptase inhibitors on HIV-1 replication capacity.
AIDS research and human retroviruses - 1 Aug 2013
Hsieh Szu-Min, Pan Sung-Ching, Chang Sui-Yuan, Hung Chien-Ching, Sheng Wang-Huei, Chen Mao-Yuan, Chang Shan-Chwen
Abstract excerpt
The effects of drug resistance on HIV-1 replication capacity have been studied, but data from clinical isolates are few. We accessed the patients with HIV-1 infection at the National Taiwan University Hospital who experienced virological failure. Genotypic susceptibility and replication capacity of clinical HIV-1 isolates were measured. There were 80 patients enrolled between September 2007 and August 2010. The...
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