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Article

Competitive fitness of nevirapine-resistant human immunodeficiency virus type 1 mutants.

Journal of virology - 1 Jan 2004

Collins Jennifer A, Thompson M Gregory, Paintsil Elijah, Ricketts Melisa, Gedzior Joanna, Alexander Louis

Abstract excerpt

Determining the fitness of drug-resistant human immunodeficiency virus type 1 (HIV-1) strains is necessary for the development of population-based studies of resistance patterns. For this purpose, we have developed a reproducible, systematic assay to determine the competitive fitness of HIV-1 drug-resistant mutants. To demonstrate the applicability of this assay, we tested the fitness of the five most common...

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Topics

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Share to Anti-HIV Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Reverse Transcriptase

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Source

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Identifiers

PMID: 14694092
DOI: 10.1128/jvi.78.2.603-611.2004
PMCID: PMC368761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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