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Virulence and Replicative Fitness of HIV-1 Transmitted/Founder (T/F) Viruses Harbouring Drug Resistance-Associated Mutation.

Viruses - 29 Nov 2024

Sonawane Aanand, Selvam Deepak, Yue Ling, Nesakumar Manohar, Vivekanandan Sandhya, Ashokkumar Manickam, Hunter Eric, Hanna Luke Elizabeth

Abstract excerpt

The biological characteristics of early transmitted/founder (T/F) variants are crucial factors for viral transmission and constitute key determinants for the development of better therapeutics and vaccine strategies. The present study aimed to generate T/F viruses and to characterize their biological properties. For this purpose, we constructed 18 full-length infectious molecular clones (IMCs) of HIV from...

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Share to Anti-HIV Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39772167
DOI: 10.3390/v16121854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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