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Article

Replication capacity, biological phenotype, and drug resistance of HIV strains isolated from patients failing antiretroviral therapy.

Journal of medical virology - 1 Jan 2003

Nicastri Emanuele, Sarmati Loredana, d'Ettorre Gabriella, Palmisano Lucia, Parisi Saverio G, Uccella Ilaria, Rianda Alessia, Concia Ercole, Vullo Vincenzo, Vella Stefano, Andreoni Massimo

Abstract excerpt

The fitness of human immunodeficiency virus (HIV) in vivo depends on the interaction of a multitude of viral and host factors. The aim of this study was to analyze the biological phenotype and the intrinsic capacity of the HIV isolates with drug-resistance mutations to replicate efficiently in the absence of drugs. An open label multicenter cross-sectional study was undertaken on 28 HIV-infected patients failing...

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Share to Anti-HIV Agents
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Gene Products, pol

Share to pol Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 12436471
DOI: 10.1002/jmv.10269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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