Article
Sexual dimorphism in the effect of GDF-6 deficiency on murine tendon.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Dec 2009
Mikic Borjana, Rossmeier Kerri, Bierwert LouAnn
Abstract excerpt
Three members of the growth/differentiation factor (GDF) subfamily of bone morphogenetic proteins (BMPs), GDFs-5, -6, and -7, have demonstrated the potential to augment tendon and ligament repair. To gain further insight into the in vivo role of these molecules, previous studies have characterized intact and healing tendons in mice with functional null mutations in GDF-5 and -7. The primary goal of the present...
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