Article
Effect of GDF-7 deficiency on tail tendon phenotype in mice.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2008
Mikic Borjana, Entwistle Rachel, Rossmeier Kerri, Bierwert Louann
Abstract excerpt
The subfamily of growth/differentiation factors (GDFs) known as GDFs 5, 6, and 7 appears to be involved in tendon maintenance and repair, although the precise nature of this role has yet to be elucidated. The aim of the present study was to examine the role of GDF-7 in tendon maintenance by studying tail tendon fascicle gene expression, composition, and material property strain rate dependency in 16-week-old male...
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