Article
Association between the IGFBP-3 rs2854744 polymorphism and cancer risk: a meta-analysis.
BMC medical genomics - 10 Apr 2026
Sun Dan, Xu Lihua, Chen Yajuan, Wang WanJu, Wang Na, Hu Gang
Abstract excerpt
BACKGROUND: Recently, the association of IGFBP-3 polymorphism and cancer risk has attracted many attentions. Previous studies have shown that IGFBP-3 rs2854744 was associated with cancer, but the results were conflicting. METHOD AND RESULTS: We performed a meta-analysis including 33 studies with 24,688 cases and 28,972 controls to seek the association among them. A significant increase of cancer risk was found...
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